創薬流通市場「薬市楽座」

安土桃山時代に自由取引市場として発展した「楽市楽座」にあやかり、創薬シーズ・技術のマーケットプラットフォームを創薬流通市場、「薬市楽座」と名付けました。このマーケットが楽市楽座のように発展することを願っています。

創薬流通市場である薬市楽座では、弊社がお預かりしている創薬シーズ・技術の情報をリストアップしています。ご興味に応じて検索していただくことが可能です。また、リストのダウンロードも行っていただけます。ご興味のあるものがあれば、お問い合わせボタンをクリックしていただき、弊社へのコンタクトをお願いいたします。追加情報を開示させていただきます。

なお、2019年6月27日より、日本語ページにおける、創薬シーズ、創薬技術の各リスト表記が英語に変更になりました。ダウンロード用のPDF、エクセルファイルは英語ページよりダウンロードできる資料と同一ですので、予めご了承下さいませ。

創薬シーズ・創薬技術一覧(PDF) 疾患領域別 創薬シーズ一覧(PDF) 創薬シーズ・創薬技術一覧(Excel)

絞り込み検索

掲載日 技術番号 技術名 技術概要
19/11/29 TGEM035 Effective platform using highly branched glucan for DDS carrier Highly branched glucan has very attractive characteristics, such as a spherical nano-sized particle, high water solubility, narrow molecular size distribution, and the numerous modifiable residues, as a dendrimer for pharmaceutical application. Established technology enables to control the average particle size of this glucan between 10 nm and 50 nm strictly, and to conjugate the functional substances, such as peptide, nucleotide, sugar chain, anticancer drug, and antibody, on the surface of its particle arbitrarily. The structural features of this polymer could permit drug delivery to specific tissues and multivalent interactions with target molecules. This glucan is an effective platform for DDS carrier such as vaccine and anticancer drug. 問合せ
19/11/05 TGEM034 Innovative platform technology for targeted delivery of therapeutics A proprietary biomimetic vector (a short peptide that binds to proteoglycan-rich tissues) can be fused with a wide variety of therapeutics (proteins, small molecules etc) and enables delivery of locally injected therapies to the hard-to-reach tissues where they are needed. Sustained therapeutic levels within the targeted tissues can increase efficacy and avoid systemic adverse events. 問合せ
19/11/05 TGEM033 Long-term sustained release microformulations This technology platform enables long-term sustained release of a drug into the blood from the administration site and treatment with once in 1 month to 6 months. The best polymer among more than 15 kinds of polymers can be proposed based on the results of feasibility studies. Opportunity for using this technology is limited to Japanese companies. 問合せ
19/09/30 TGEM032 Cell Therapy technology platform for developing cell-based products for multiple chronic diseases
Novel and propreitary cell therapy platform technology that can be used for the development of cellular therapies. Cellular therapies are the new modality of treatment that provides long-term cures for chronic diseases. This platform can be applied across multiple disease areas-musculoskeletal disorders,urogynacology, oncology,cardiology. Three pronged approach to tackle degenerative diseases through drug/biologic/device mechanisms. 問合せ
19/08/21 TGEM031 Delivery of anticancer drugs to cancer cells
TGEM031 is a modified β-Cyclodextrin and increased in vitro antitumor activities of doxorubicin (DOX), vinblastine and paclitaxel. The complex of DOX with TGEM031 markedly increased antitumor activity of DOX, after intravenous administration to tumor-bearing mice. 問合せ
19/07/31 TGEM030 Innovative technology enabling improved GI absorption of the insoluble drug
A patented technology based on lipidic compositions which form optimal dispersed phase in the gastrointestinal environment for improved absorption of the insoluble drug. TGEM030 enables development of superior oral products with: Improved solubilization and high drug loading capacity, improved bioavailability, faster and more consistent absorption leading to reduced variability and reduced sensitivity to food effects. TGEM030 utilizes bioacceptable excipients and conventional manufacturing processes.
問合せ
19/07/08 TGEM029 Sustained release PLGA
Poly lactide-co-glycolide acid (PLGA) microsphere technology for sustained release of drugs. Versatile drug release profiles could be achieved by adjusting the formulation compositions and effective plasma drug concentration could be maintained for several weeks or months upon one injection. In addition, the pharmacokinetic and pharmacodynamics evaluation models for sustained release technology have been established which could speed up product development. 問合せ
19/07/08 TGEM028 Posterior eye delivery
An ocular delivery technology specially designed to topically deliver hydrophobic small molecular across ocular tissues into posterior ocular tissues.
The eye drop based delivery technology can overcome the delivery obstacle of tissue barriers to transport therapeutics to posterior ocular target tissue. This breakthrough technology is expected to bring broader applications for posterior ocular drug delivery
問合せ
19/07/08 TGEM027 Site-specific linker toxin
The disadvantages of traditional conjugation technologies include the lack of specificity at the connecting positions of the antibodies and the variable number of connections. The new technology can overcome these disadvantages by improving homogeneity of ADC via site-specific conjugation. The site-specific linker-toxin shows better homogeneity, stability and efficacy. 問合せ
19/07/08 TGEM026 Intracellular delivery
This technology enables peptide and oligonucleotide drugs to be delivered efficiently into cells through conjugating a cell-penetrating motif (CPM) onto drug candidate. Unlike liposomal or other nanoparticle formulation, the CPM technology requires no encapsulation process and provides formulated drug product with high stability and storage condition tolerances. 問合せ